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Floating thrombus- basilar artery occlusion

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Abstract

Aim

The treatment of Basilar artery occlusion (BAO) with low NIHSS score requires to be individualized to each patient

Background

Basilar artery occlusion represents a small proportion of strokes worldwide but can have catastrophic presentations. Recent trials for BAO have studied the benefits of endovascular treatment (EVT) over intravenous thrombolysis (IVT) and have concluded that EVT has better mortality and morbidity outcomes. However, the management of BAO with lower NIHSS scores may become risky as the complications of the said treatment may outweigh the benefits.

Case description

We present a 54-year-old lady who presented with dizziness and hemiplegia which resolved within 1 hour. She had hypertension, mild left facial weakness and NIHSS score of 1 on presentation. MRI Brain revealed an acute focal left lateral medullary infarct, and angiogram showed a basilar artery thrombosis with distal basilar artery flow. She was started on dual antiplatelet therapy, low molecular weight heparin and statin. Cerebral DSA revealed a floating thrombus within the basilar artery and left vertebral artery V4 segment stenosis with normal flow in the distal basilar artery. As the patient had mild symptoms, she was discharged on oral anticoagulant and single antiplatelet therapy. She underwent stenting of the Vertebral artery V4 segment, 2 months later as she had recurrent posterior circulation transient ischemic attacks. 

Conclusion

All basilar artery occlusions need not require immediate endovascular thrombectomy and may be managed conservatively initially with anti-coagulation and antiplatelet therapy.

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References

References

1. Schonewille WJ, Wijman CA, Michel P, et al. Treatment and outcomes of basilar artery occlusion: results from the BASICS registry. Neurology. 2009;73(24):2008-2015.

2. Caplan LR. Posterior circulation ischemia: then, now, and tomorrow. Stroke. 2000;31(8):2011-2023.

3. Powers WJ, Rabinstein AA, Ackerson T, et al. Guidelines for the early management of patients with acute ischemic stroke. Stroke. 2019;50(12):e344-e418.

4. Saver JL. Clinical practice: acute ischemic stroke. N Engl J Med. 2011;365(7):654-663.

5. Lindsberg PJ, Mattle HP. Therapy of basilar artery occlusion: a systematic analysis. Stroke. 2006;37(3):922-928.

6. Wang Y, Wang Y, Zhao X, et al. Clopidogrel with aspirin in acute minor stroke or TIA (CHANCE). N Engl J Med. 2013;369(1):11-19.

7. Johnston SC, Easton JD, Farrant M, et al. Clopidogrel and aspirin in acute ischemic stroke and TIA (POINT). N Engl J Med. 2018;379(3):215-225.

8. Diener HC, Foerch C, Riess H, et al. Secondary prevention of ischemic stroke in patients with atrial fibrillation. Lancet Neurol. 2014;13(4):375-388.

9. Chimowitz MI, Lynn MJ, Derdeyn CP, et al. Stenting versus aggressive medical therapy for intracranial arterial stenosis. N Engl J Med. 2011;365(11):993-1003.

10. Mattle HP, Arnold M, Lindsberg PJ, et al. Basilar artery occlusion. Lancet Neurol. 2011;10(11):1002-1014.

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