Case Report Rare presentation of CNS manifestation of pseudo inflammatory tumor which responded to steroid: Rare presentation of CNS manifestation of pseudo inflammatory tumor
Authors
Nitin Rathod, ANDREA JANICE FONSECA, Shweta Thadeshwar, Prachi WaghmareFiles
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Journal
Published in Vol. 2024 No. 66 (4) of Bombay Hospital Journal.
Bombay Hospital Journal (BHJ) is a peer-reviewed quarterly published Print and Online journal. It is an official Journal of Bombay Hospital institute of medical sciences. The aim of BHJ is to improve medical care by publishing sound scientific articles (both research and practice papers) and focusing on topics that are of great importance to its readership.
Editor-in-Chief- Dr Satish Vasant Khadilkar
About the JournalAbstract
Abstract:
Aim- Rare presentation of CNS manifestation of pseudo inflammatory tumor which responded to steroid.
Background- Inflammatory pseudotumor are rare, benign, tumor-like lesions characterized by chronic inflammatory cell infiltration, which can mimic malignant tumors both clinically and radiologically.
Case Description- Here, we present a case of a patient diagnosed with an inflammatory pseudotumor involving the left 7th and 8th cranial nerves, who presented with symptoms of severe headache, recurrent vomiting, dizziness, and gait ataxia. Initial examination revealed no fever or other systemic symptoms, and MRI imaging showed enhancement along the left 7th and 8th nerve complex.
Conclusion-Elevated serum IgG4 levels supported an inflammatory etiology, while cerebrospinal fluid (CSF) analysis and other tests ruled out infection or malignancy. The patient showed significant improvement in symptoms after corticosteroid therapy with IV dexamethasone and supportive care
Clinical Significance-This case highlights the diagnostic challenge posed by inflammatory pseudotumor in cranial nerves and underscores the importance of distinguishing them from other lesions to guide appropriate treatment.
References
References:
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Saifudheen K., Jose J., Gafoor V.A: Inflammatory pseudotumor of the head presenting with hemiparesis and aphasia. Case Rep Neurol Med 2011; 2011: pp. 1-4.
Patnana M., Sevrukov A.B., Elsayes K.M., et. al.: Inflammatory pseudotumor: the great mimicker. AJR Am J Roentgenol 2012; 198: pp. W217-W227.
Ortlip T.E., Drake V.E., Raghavan P., et. al.: Inflammatory pseudotumor of the temporal bone: a case series. Otol Neurotol 2017; 38: pp. 1024-1031.
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