Case Report Metastatic mammary lobular carcinoma presenting with ileal obstruction: A Case Report : Ileal metastasis in mammary lobular carcinoma

Shrutika Jadhav

doi:10.15713/ins.bhj.170

Authors

Shrutika Jadhav

DOI:

https://doi.org/10.15713/ins.bhj.170

Keywords:

intestinal metastasis, breast cancer, ileal obstruction

Abstract

Abstract:

Aim: The aim of this article is to present a rare case of ileal metastasis from lobular mammary carcinoma.

Background: Breast cancer has the highest incidence among women and is prone to develop distant metastasis. Metastasis to the gastrointestinal (GI) tract is rare and occurs more frequently in invasive lobular carcinoma. Patients may be asymptomatic or present with variable vague symptoms that may be mistakenly attributed to side effects of chemotherapy or other benign GI diseases.

Case Description: This case report describes a 78-year-old Indian female patient with bilateral lobular mammary cancer who presented with ileal obstruction.

Conclusion: Metastatic lobular mammary carcinoma has a wide range of clinical presentations. Adequate procedures should be performed promptly to obtain histological diagnosis. The possibility of intestinal involvement by metastasis should be considered in a known case of breast carcinoma with acute abdominal symptoms.

Clinical Significance: Increased awareness of bowel metastasis secondary to breast cancer and a thorough understanding of the clinical and histological features, are fundamental to avoid delay in diagnosis and management.

References

● References

B. G. Taal, H. Peterse, and H. Boot, “Clinical presentation, endoscopic features, and treatment of gastric metastases from breast carcinoma,” Cancer, vol. 89, pp. 2214–2221, 2000.

GRAHAM WP 3rd. GASTRO-INTESTINAL METASTASES FROM CARCINOMA OF THE BREAST. Ann Surg. 1964 Mar;159:477-8.

Budzyński P, Pędziwiatr M, Kenig J, Lasek A, Winiarski M, Major P, et al. Gastrointestinal obstruction in patients previously treated for malignancies. Pol Przegl Chir 2016;88:93-8.

Idelevich E, Kashtan H, Mavor E, Brenner B. Small bowel obstruction caused by secondary tumors. Surg Oncol (2006) 15(1):29–32. doi: 10.1016/ j.suronc.2006.05.004

Ambroggi M, Stroppa EM, Mordenti P, Biasini C, Zangrandi A, Michieletti E, Belloni E, Cavanna L. Metastatic breast cancer to the gastrointestinal tract: report of five cases and review of the literature. Int J Breast Cancer. 2012;2012:439023. doi: 10.1155/2012/439023. Epub 2012 Oct 4. PMID: 23091732; PMCID: PMC3471430.

Zheng Y, Zhao Q. Metastatic tumors in the small bowel: A report of 3 cases. Chin J Clin Oncol (1990) 17(02):78–9

Lee MH, Zaheer A, Voltaggio L, Johnson PT, Fishman EK. Clinical time course and CT detection of metastatic disease to the small bowel. Abdom Radiol (NY). (2019) 44(6):2104–10. doi: 10.1007/s00261-019-01957-w

Arrangoiz, R., Papavasilious, P., Dushkin, H. and Frama, J.M. (2011) Case Report and Literature Review: Metastatic Lobular Carcinoma of the Breast an Unusual Presentation. International Journal of Surgery Case Reports, 2, 301-305.

Cervi G, Vettoretto N, Vinco A, Cervi E, Villanacci V, Grigolato P, Giulini SM. Rectal localization of metastatic lobular breast cancer: report of a case. Dis Colon Rectum 2001; 44: 453-455 [PMID: 11289296 DOI: 10.1007/BF02234749]

Dossus L, Benusiglio PR. Lobular breast cancer: incidence and genetic and non- genetic risk factors. Breast Cancer Res (2015) 17:37. doi: 10.1186/s13058-015-0546-7

Christgen M, Steinemann D, Kühnle E, Länger F, Gluz O, Harbeck N, et al. Lobular breast cancer: Clinical, molecular and morphological characteristics. Pathol Res Pract (2016) 212(7):583–97. doi: 10.1016/j.prp.2016.05.002