METASTATIC NEUROENDOCRINE TUMOR OF THE OVARY - AN UNUSUAL SITE
METASTATIC NEUROENDOCRINE TUMOR OF THE OVARY - AN UNUSUAL SITE
DOI:
https://doi.org/10.15713/ins.bhj.94Keywords:
lung, neuroendocrine tumor, metastatic ovarian massesAbstract
A 22 year old female with stage III small cell neuroendocrine carcinoma of the lung presented two years later with a large abdomino-pelvic mass. Core biopsy showed a metastatic high-grade neuroendocrine carcinoma. She responded poorly to chemotherapy. An exploratory laparotomy revealed bilateral large ovarian masses. Total hysterectomy with bilateral salpingo-oophorectomy was performed. Histopathology showed a metastatic high grade neuroendocrine carcinoma of both ovaries, consistent with metastasis from small cell neuroendocrine carcinoma of the lung. Post adjuvant chemotherapy she remained controlled over four years. We present a rare case of small cell neuroendocrine tumor of the lung with metastasis to the ovary.
References
Modlin IM, Lye KD, Kidd M. A 5-decade analysis of 13,175 carcinoid tumors.
Cancer. 2003; 97(4):934-59.
Godwin JD. Carcinoid tumors. An analysis of 2,837 cases. Cancer.1975; 36(2):560-9.
Michiko Kaiho-Sakuma, Masafumi Toyoshima Aggressive neuroendocrine tumor of
the ovary with multiple metastases treated with everolimus: A case report Gynecol
Oncol Rep 2018 Feb; 23: 20–23.
Subhashis Mitra, Amiya Jhunjhunwala. Bilateral ovarian metastases as the presenting
manifestation of lung carcinoid in a 50year –old woman: case study and review of
literature. Ind. J Pathol Microbiol, July –Sept 2017; 60(3): 396-398.
J Kupryjanczyk. Neuroendocrine Tumor of the Ovary - A Review. Verh Dtsch Ges
Pathol, 1997; 81; 253-259.
Householder J, Han A, Edelson MI. Immunohistochemical confirmation of pulmonary
papillary adenocarcinoma metastatic to ovaries. Arch Pathol Lab Med 2002; 126:1101-3.
Yeh KY, Chang JW, Hsueh S. Ovarian Metastasis Originating from Broncheoalveolar
Carcinoma: A Rare Presentation of Lung Cancer. Japanese Journal of Clinical Oncology,
; Vol 33: 404-7.
Yun Kyunk Kang. Ovarian and Pituitary Metastasis from Adenocarcinoma of the lung- A
case report. Korean Journal of Pathology, 2006; Vol 40:452-5.
Oneda E, Zorzi F, Gorio A. Differential Diagnosis of Small Cell Carcinoma of the Ovary
or Ovarian Metastases of Small Cell Carcinoma of the Lung: A Case Report and Review of
the Literature. Case Rep Oncol 2020; 13:822–828
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Bombay Hospital Journal

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.