Article SKIN ADNEXAL ADENOCARCINOMA: CASE OF A RARE MALIGNANT CUTANEOUS TUMOUR
SKIN ADNEXAL ADENOCARCINOMA: CASE OF A RARE MALIGNANT CUTANEOUS TUMOUR
Keywords:
Skin adnexal tumors, adenocarcinoma , Eccrine, Apocrine, ChemotherapyAbstract
Background: Skin tumors comprise of innumerable benign and malignant lesions. They vary in behaviour and malignant potential. Apart from more common melanomatous and squamous cell carcinomas, there exist unexplored arena of adnexal tumors that are rare and most often pose a dilemma for treating doctor. Their demography and presentation are yet to be standardized globally.
Because of its rarity, the diagnosis is challenging and often impossible to distinguish from metastatic cutaneous adenocarcinoma of the breast. The standard of care remains surgery for resectable disease. To date, univocal guidelines for metastatic disease are lacking, particularly regarding systemic therapy. We report a clinical case of a patient diagnosed with cutaneous adnexal adenocarcinoma of the right supraclavicular region without lymph node and bone metastasis.
References
Martinez SR, Barr KL, Canter RJ. Rare tumors through the looking glass: an examination of malignant cutaneous adnexal tumors. Arch Dermatol. 2011;147:1056-62.
Boit LPE, editor. Pathology and genetics of skin tumors. IARC; 2006.
Danialan R, Mutyambizi K, Aung P, Prieto VG, Ivan D. Challenges in the diagnosis of cutaneous adnexal tumours. J Clin Pathol. 2015;68(12):992–1002.
Storm CA, Seykora JT. Cutaneous adnexal neoplasms. Am J Clin Pathol. 2002;118 Suppl:S33–49.
Fernandez-Flores A. The elusive differential diagnosis of cutaneous apocrine adenocarcinoma vs. metastasis: the current role of clinical correlation. Acta Dermatovenerol Alp Pannonica Adriat. 2009;18(3):141–2.
Piedbois P, Breau JL, Morere JF, Israel L. Sweat gland carcinoma with bone and visceral metastases. Prolonged complete remission lasting 16 months as a result of chemotherapy. Cancer. 1987;60(2):170–2.
Tlemcani K, Levine D, Smith RV, Brandwein-Gensler M, Staffenberg DA, Garg MK, et al. Metastatic apocrine carcinoma of the scalp: prolonged response to systemic chemotherapy. J Clin Oncol. 2010;28(24):e412–4.
Chamberlain RS, Huber K, White JC, Travaglino-Parda R. Apocrine gland carcinoma of the axilla: review of the literature and recommendations for treatment. Am J Clin Oncol. 1999;22(2):131–5.
Ogata D, Kiyohara Y, Yoshikawa S, Kasami M. Treatment strategy for cutaneous apocrine carcinoma. Int J Clin Oncol. 2014;19:712-5.
Romeu M, Foletti JM, Chossegros C, Dales JP, Berbis P, Cribier B, et al. Malignant cutaneous adnexal neoplasms of the face and scalp: diagnostic
and therapeutic update. J Stomatol Oral Maxillofac
Surg. 2017;118:95-102.
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