A Curious Case of Ileocaecal Mass: A Curious Case of Ileocaecal Mass
Authors
Dr. Sanjay ChatterjeeFiles
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Journal
Published in Vol. 67 No. 3 (2025) of Bombay Hospital Journal.
Bombay Hospital Journal (BHJ) is a peer-reviewed quarterly published Print and Online journal. It is an official Journal of Bombay Hospital institute of medical sciences. The aim of BHJ is to improve medical care by publishing sound scientific articles (both research and practice papers) and focusing on topics that are of great importance to its readership.
Editor-in-Chief- Dr Satish Vasant Khadilkar
About the JournalAbstract
Background: Neuroendocrine tumours (NETs) of the ileocaecal junction are uncommon neoplasms and are frequently diagnosed
incidentally. Most gastrointestinal NETs are detected on histopathological examination following surgery for presumed benign
conditions such as appendicitis. Surgical resection remains the cornerstone of management, with the extent of surgery determined by
tumour size, location, and pathological features.
Case Presentation: We report the case of a 46-year-old male who presented with recurrent abdominal pain, vomiting, and significant
weight loss. Radiological evaluation revealed an ileocaecal mass causing luminal narrowing and features of subacute intestinal
obstruction. A CT-guided biopsy suggested a low-grade neuroendocrine tumour. The patient underwent a radical right hemicolectomy.
Histopathological and immunohistochemical evaluation confirmed a well-differentiated Grade 1 neuroendocrine tumour involving
the ileocaecal junction, terminal ileum, and appendix, with regional lymph node metastasis.
Conclusion: This case highlights the diagnostic challenge posed by ileocaecal neuroendocrine tumours due to their nonspecific
presentation. Routine histopathological examination of appendectomy and right hemicolectomy specimens is essential, as clinically
occult malignancies and NETs may otherwise be missed.
References
1. Masson E. Tumeurs endocrines digestives: stratégie
diagnostique [Internet]. EM-Consulte; 2022 [cited 2022
Apr 22]. Available from: https://www.em-consulte.com/
article/132721/tumeurs-endocrines-digestives-strategiediagnostic
2. G A. Tumeurs endocrines de l’appendice. Presse Med.
1914;22:37-40.
3. Scoazec JY, Couvelard A. The new WHO classification
of digestive neuroendocrine tumors. Ann Pathol.
2011;31(2):88-92.
4. Modlin IM, Sandor A. An analysis of 8305 cases of
carcinoid tumors. Cancer. 1997;79(4):813-829.
5. Maggard MA, O’Connell JB, Ko CY. Updated
population-based review of carcinoid tumors. Ann Surg.
2004;240(1):117-122.
6. Pape UF, Perren A, Niederle B, Gross D, Gress T, Costa F,
et al. ENETS consensus guidelines for the management of
patients with neuroendocrine neoplasms from the jejunoileum
and the appendix including goblet cell carcinomas.
Neuroendocrinology. 2012;95(2):135-156.
7. Pawa N, Clift AK, Osmani H, Drymousis P, Cichocki
A, Flora R, et al. Surgical management of patients with
neuroendocrine neoplasms of the appendix: appendectomy
or more. Neuroendocrinology. 2018;106(3):242-251.
8. Lloyd RV, Osamura RY, Klöppel G, Rosai J. WHO
classification of tumours of endocrine organs [Internet].
Lyon: IARC; 2017 [cited 2022 Apr 22]. Available from:
https://publications.iarc.fr/Book-And-Report-Series/
Who-Classification-Of-Tumours/WHO-Classification-
Of-Tumours-Of-Endocrine-Organs-2017
9. Kaltsas GA, Besser GM, Grossman AB. The diagnosis
and medical management of advanced neuroendocrine
tumors. Endocr Rev. 2004;25(3):458-511.
10. Tchana-Sato V, Detry O, Polus M, Thiry A, Detroz B,
Maweja S, et al. Carcinoid tumor of the appendix: a
consecutive series from 1237 appendectomies. World J
Gastroenterol. 2006;12(41):6699-6701.
11. Goede AC, Caplin ME, Winslet MC. Carcinoid tumour of
the appendix. Br J Surg. 2003;90(11):1317-1322.
12. Panzuto F, Di Fonzo M, Iannicelli E, Sciuto R, Maini
CL, Capurso G, et al. Long-term clinical outcome of
somatostatin analogues for treatment of progressive,
metastatic, well-differentiated entero-pancreatic endocrine
carcinoma. Ann Oncol. 2006;17(3):461-466.
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