LARGE DUODENAL GIST WITH COURSE OVER 5 YEARS AND IT’S MANAGEMENT: A CASE REPORT.
Keywords:
Gastrointestinal stromal tumor, duodenum, Imatinib, pancreatoduodenectomyAbstract
ABSTRACT: Gastrointestinal stromal tumor (GIST) is a rare type of neoplasm of the gastrointestinal (GI) tract. Because of the rarity of occurrence, there is not much literature available. Existing literature is in the form of either case report or small case series. This is a case report of a large duodenal GIST diagnosed in 2014. After evaluation and surgical opinion at outside hospital the patient was started on chemotherapy. Patient was non-compliant with the chemotherapy, taking it on and off from 2014 to 2019. In 2019 he was operated with pancreatoduodenectomy at our center and has been on routine follow-up since. Duodenal GIST has anatomical complexities with close proximity to noble structures, there is a lack of consensus on appropriate surgical treatment, prognostic factors and survival which constitute a subject of controversy.
References
Yang F, Jin C, Du Z, Subedi S, Jiang Y, Li J, et al. Duodenal gastrointestinal stromal tumor: Clinicopathological characteristics, surgical outcomes, long term survival and predictors for adverse outcomes. Am J Surg. 2013; 206: 360-367.
Beham A, Schaefer IM, Cameron S, von Hammerstein K, Fuzesi L, Ramadori G, et al. Duodenal GIST: a single center experience. Int J Colorectal Dis. 2013;28(4):581-90.
Sawaki A. Rare gastrointestinal stromal tumours (GIST): omentum and retroperitoneum. Transl Gastroenterol Hepatol 2017;2:116.
Sugase T, Takahashi T, Nakajima K, Hirota S, Musuzawa T, Nishida T, et al. Clinicopathological characteristics, surgery and survival outcomes of patients with duodenal gastrointestinal tumours. Digestion. 2016;94(1):30-6.
Johnston FM, Kneuertz PJ, Cameron JL, Sanford D, Fisher S, Turley R, et al. Presentation and management of gastrointestinal stromal tumours of the duodenum: A multi-institutional analysis. Ann Surg Oncol. 2012; 19: 3351-3360.
Shen C, Chen H, Yin Y, et al. Duodenal gastrointestinal stromal tumors: clinicopathological characteristics, surgery, and long-term outcome. BMC Surg 2015;15: 98.
Rabin I, Chikman B, Lavy R, et al. Gastrointestinal stromal tumors: a 19 year experience. Isr Med Assoc J 2009;11: 98-102.
Boselli C, Cirocchi R, Gemini A, et al. Urgency surgical treatment for duodenal GISTs: analysis of aged patients and review of the literature. Aging Clin Exp Res 2017;29: 1-6.
Chok AY, Koh YX, Ow MY, et al. A systematic review and meta-analysis comparing pancreatoduodenectomy versus limited resection for duodenal gastrointestinal stromal tumors. Ann Surg Oncol 2014;21:3429-38.
Y. Huang et al. / European Journal of Surgical Oncology 45 (2019) 1950-1956.
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